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Cheesy Pepperoni Pizza Biscuit Casserole 🍕🧀

🍕🧀 Cheesy Pepperoni Pizza Biscuit Casserole – An Easy Family Favorite!

What happens when fluffy biscuits meet cheesy pizza goodness? You get this irresistible Cheesy Pepperoni Pizza Biscuit Casserole! 😍

Packed with seasoned ground beef, zesty pizza sauce, savory pepperoni, fluffy biscuit pieces, and loads of gooey melted mozzarella, this easy casserole brings all your favorite pizza flavors together in one delicious dish.

It’s warm, cheesy, filling, and perfect for busy weeknights when everyone is craving something comforting! ❤️

🛒 Ingredients

  • 🥫 1 can (16 oz) refrigerated biscuit dough
  • 🥩 1 lb ground beef
  • 🍕 1 cup pizza sauce
  • 🥓 1 cup sliced pepperoni
  • 🧀 2 cups shredded mozzarella cheese
  • 🧄 1 teaspoon garlic powder
  • 🌿 1 teaspoon Italian seasoning
  • 🧅 ½ teaspoon onion powder
  • 🫒 1 tablespoon olive oil, if needed
  • 🧂 Salt and black pepper, to taste
  • 🧀 ¼ cup grated Parmesan cheese (optional)

👩‍🍳 Instructions

1. Preheat the oven

Preheat your oven to 375°F (190°C). Lightly grease a 9 × 13-inch baking dish.

2. Cook the ground beef

In a large skillet over medium heat, cook the ground beef until browned and fully cooked. Drain any excess grease, then stir in the garlic powder, onion powder, Italian seasoning, salt, and black pepper.

3. Prepare the biscuit pieces

Cut the refrigerated biscuit dough into bite-sized pieces. Place them in a large bowl and gently toss with the pizza sauce until coated.

4. Assemble the casserole

Add the seasoned beef and sliced pepperoni to the biscuit mixture. Stir gently, then transfer everything to the prepared baking dish. Sprinkle the mozzarella evenly over the top and finish with Parmesan if desired.

5. Bake until bubbly

Bake for approximately 25–35 minutes, until the cheese is melted and golden and the biscuit pieces are cooked through in the center. If the cheese browns too quickly, loosely cover the dish with foil.

6. Rest and serve

Let the casserole rest for 5 minutes before serving. Garnish with a little fresh parsley or extra Italian seasoning for that finishing touch! 🍽️

💡 Tips for the Best Pizza Biscuit Casserole

✨ Try different toppings: Mushrooms, diced bell peppers, black olives, or cooked sausage make delicious additions.

✨ Make it extra cheesy: Add a little cheddar or provolone along with the mozzarella.

✨ Keep the biscuits fluffy: Cut the dough into evenly sized pieces and check the center carefully to ensure the biscuits are fully baked.

✨ Add a little heat: Sprinkle in red pepper flakes for a spicy pizza-inspired kick.

✨ Serve it with a side: A crisp green salad, roasted vegetables, or warm garlic bread makes this a complete family meal.

❤️ The Ultimate Cheesy Comfort Food!

This casserole combines the fun of pizza with the cozy goodness of a homemade baked dinner. With simple ingredients, easy preparation, and plenty of melted cheese, it’s a great option for family dinners, casual get-togethers, or a fun Friday night meal.

Serve it hot, pull apart those cheesy biscuit pieces, and enjoy every delicious bite! 🤤🍕🧀

👇 Tell us: Would you make yours with classic pepperoni, spicy sausage, or ALL the pizza toppings? ❤️

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